Season 1 Edit
- Jor-El - Killed in the destruction of Krypton.
- Lara Van-El - Killed in the destruction of Krypton.
- Zor-El - Killed in the destruction of Krypton.
- Alura Zor-El - Killed in the destruction of Krypton.
- Vartox - Stabbed himself with a piece of his axe to evade capture.
Stronger Together Edit
- Hellgrammite - Stabbed by Alex with his own stinger.
Fight or Flight Edit
- Alyssa Krull - Died of radiation exposure in the meltdown of the Bakerline Nuclear Power Station.
How Does She Do It? Edit
- Ethan Knox - Blew himself up with a suicide vest on Lord's orders.
Red Faced Edit
- T.O. Morrow - Shot by Alex.
- Red Tornado - Obliterated by Kara with her laser beams.
Human for a Day Edit
- Agent Reynolds - Killed offscreen by Jemm.
- Agent Tsung - Killed offscreen by Jemm.
- Agent Donovan - Neck snapped by Jemm.
- Jemm - Neck snapped by J'onn.
For the Girl Who Has EverythingEdit
- Black Mercy - Shriveled up after Kara rejected it.
- General Astra - Stabbed in the heart by Alex with a Kryptonite sword.
Truth, Justice and the American Way Edit
- Gabriel Phillips/Prisoner 2444 - Decapitated by Draper's guillotine,
- Jim Warren - Shot by Draper.
- Brainiac 8/Indigo - Obliterated by Winn when he uploaded his virus into her. Non later rebuilt her with the Omegahedron.
- Kelly - Jumped off of a building while under Myriad's control.
Better Angels Edit
- Brainiac 8/Indigo - Ripped in half by J'onn.
Crisis on Earth-X, Part 1Edit
- James Olsen/Guardian - Earth X - Shot in the chest with an arrow by the Oliver of Earth-X.